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The quadruple marker test, also known as the quad screen test, is a blood test that is used during pregnancy to assess the risk of certain genetic conditions and birth defects in the developing fetus. The test is typically done between weeks 15 and 20 of pregnancy.
The quadruple marker test measures levels of four different substances in the mother's blood:
Alpha-fetoprotein (AFP)
Human chorionic gonadotropin (HCG)
Estriol
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Abnormal levels of these substances can be associated with an increased risk of certain conditions, such as Down syndrome, neural tube defects, and other chromosomal abnormalities.
It's important to note that the quadruple marker test is a screening test, not a diagnostic test. This means that it can provide an indication of whether there is an increased risk of a certain condition, but it cannot provide a definitive diagnosis. If the test results indicate a higher risk of a genetic condition, your doctor may recommend further testing, such as an amniocentesis or chorionic villus sampling (CVS), to confirm or rule out the diagnosis.
There is no specific preparation required for the quadruple marker test. However, it's a good idea to talk to your doctor about any concerns you may have and to understand the potential risks and benefits of the test before proceeding.
This blood test is used to screen for certain birth defects, such as Down syndrome, neural tube defects, and abdominal wall defects. It may be recommended for women who are pregnant and have risk factors for these conditions.
The report is usually available within a day or two.
Typically requires a visit to a diagnostic center or a laboratory for the test.
Fasting is usually not required for this test.